Pest that killed people for over 500 years had a deeper impact on humanity than any other infection. Its effect in economy, society and culture can be equally established. In 1347 the infection stooped on Europe in extreme waves. These changed the life and culture of Europe radically. Until the beginning of the 19th century, pest attacked all over again. The consequence of it was not only obvios in public health, medicine but also in religion, methods of burial, economy, society, as well as art and its methods.